Alpha-Stim Smart ProbesTreating pain with the
Alpha-Stim® M using microcurrent therapy

No Matter the Source, Your Patients Need Relief.

The Alpha-Stim® M provides Microcurrent Electrical Therapy (MET). It uses a low-level electrical current with a patented waveform, featured only in Alpha-Stim technology, that has been proven to assist with chronic pain management, acute pain management, and post traumatic pain management. Alpha-Stim has an extensive safety record, with only mild and self-limiting side effects (primarily skin irritation at the electrode sites in fair skinned people) and considerable scientific evidence of the significant results patients may achieve.

LET NOTHING STOP THEM.

Treating pain with the
Alpha-Stim® M using microcurrent therapy

No Matter the Source, Your Patients Need Relief.

The Alpha-Stim® M provides Microcurrent Electrical Therapy (MET). It uses a low-level electrical current with a patented waveform, featured only in Alpha-Stim technology, that has been proven to assist with chronic pain management, acute pain management, and post traumatic pain management. Alpha-Stim has an extensive safety record, with only mild and self-limiting side effects (primarily skin irritation at the electrode sites in fair skinned people) and considerable scientific evidence of the significant results patients may achieve.

LET NOTHING STOP THEM.

Buy Now

Two modalities, three ways to treat

The Alpha-Stim M system includes handheld probes or attachable electrodes for site-specific MET pain therapy, as well as earclips that provide Cranial Electrotherapy Stimulation (CES)—to relieve common comorbidities associated with pain (anxiety, depression, and insomnia) following pain treatment.
  • Alpha-Stim can be used as a first-line therapy for pain management, or as an adjunct to pharmacotherapy without polypharmacy effects
  • Alpha-Stim technology is safe, with no serious adverse events reported in over 30 years of clinical use
  • Alpha-Stim treatments are cumulative; however, most patients show at least some improvement after the first treatment
Learn More

The fundamentals: An electrical intervention

  • The brain and nervous system function electrochemically and can be readily modulated by electrical intervention1,2
  • Alpha-Stim microcurrent electrical therapy and cranial electrotherapy stimulation impacts electrochemical function at the cellular level to reduce pain related to a variety of causes

The Alpha-Stim microcurrent treatment advantage: A patented waveform

  • The only rigorously tested waveform designed and refined to improve effectiveness
  • Delivers a very low level of current in pulsed microcurrents of less than one milliampere
  • Effectively targets cell receptors, activating them through frequency matching in a manner similar to chemical ligands
VIEW PRODUCT BROCHURE

(multilingual options available)

Non-addictive pain management option

Alpha-Stim technology is a non-addictive electrical stimulation therapy that is a treatment solution for patients who:

  • Are addicted to, or at risk of, addiction to opiates
  • Have drug interaction risk factors
  • Have vocational restrictions on narcotic use
  • Are elderly
  • At risk due to compromised organ systems
  • Are medication resistant

As a leader in electrotherapy, Alpha-Stim has helped clinicians around the world offer fast, safe, and effective relief for patients suffering from pain from multiple sources, and other conditions associated with pain.

Clinical Studies

Morrow DJ, Fischer EP, Walder AM, Jubran NI. Nonopioid Alternatives to Addressing Pain Intensity: A Retrospective Look at Two Noninvasive Pain Treatment Devices. Federal Practitioner. 2019, 36(4):181-187. Download Article

Yennurajalingam S, Kang D-H, Hwu W-J, Padhye NS, Masino C, Dibaj SS, Liu DD, Williams JL, Lu Z, Bruera E. Cranial electrotherapy stimulation for the management of depression, anxiety, sleep disturbance, and pain in patients with advanced cancer: a preliminary study. Journal of Pain and Symptom Management.  2018, 55(2): 198–206. Download Abstract

Kirsch TB, Kuhn J, Price LR, Marksberry J, Haltiwanger SG. A novel medical device that relieves anxiety, depression and pain while improving sleep in a population of teachersJournal of Depression and Anxiety. 2019; 8:334. Download Article

Taylor, Ann Gill, Anderson, Joel G., Riedel, Shannon L., Lewis, Jante E., Kinser, Patricia A., and Bourguignon, Cheryl. Cranial electrical stimulation improves symptoms and functional status in individuals with fibromyalgia. Pain Management Nursing. 2013 Dec;14(4):327-335. Download article

Taylor, Ann Gill, Anderson, Joel G., Riedel, Shannon L., Lewis, Janet E. and Bourguignon, Cheryl. A randomized, controlled, double-blind pilot study of the effects of cranial electrical stimulation on activity in brain pain processing regions in individuals with fibromyalgia. Explore. 2013; 9(1):32-40. Download article

Tan, Gabriel, Rintala, Diana, Jensen, Mark P., Richards, J. Scott, Holmes, Sally Ann, Parachuri, Rama, Lashgari-Saegh, Shamsi and Price, Larry R. Efficacy of cranial electrotherapy stimulation for neuropathic pain following spinal cord injury: a multi-site randomized controlled trial with a secondary 6-month open-label phase. The Journal of Spinal Cord Medicine. 2011; 34(3):285-296. Download article

Tan, Gabriel, Rintala, Diana H., Thornby, John, Yang, June, Wade, Walter, and Vasilev, Christine. Using cranial electrotherapy stimulation to treat pain associated with spinal cord Injury.Journal of Rehabilitation Research and Development. 2006; 43(4):461-474. Presented at the South Central VA Health Care Network’s Pain Management Initiative 2nd Annual Pain Management Symposium: Campaign Against Pain. Jackson, Mississippi, April 7, 2006. Download Article

Cork, Randall C., Wood, Patrick, Ming, Norbert, Shepherd, Clifton, Eddy, James, Price, Larry The effect of cranial electrotherapy stimulation (CES) on pain associated with fibromyalgia. The Internet Journal of Anesthesiology.  2004; 8(2). Download Article

Tan, G., Rintala, D., Herrington, R., Yang, J., Wade, W., Vasilev, C. and Shanti, B.F. Treating spinal cord injury pain with cranial electrotherapy stimulation. Journal of Spinal Cord Medicine. 2003; 26(3). Poster presented at the Annual Meeting of the American Paraplegia Society, Las Vegas, Nevada, September 2-4, 2003. Download Poster

Lichtbroun, Alan S., Raicer, Mei-Ming C., and Smith, Ray B. The treatment of fibromyalgia with cranial electrotherapy stimulation. Journal of Clinical Rheumatology. 2001; 7(2):72-78. Presented at the Fifteenth Annual International Symposium on Acupuncture and Electro-Therapeutics, Columbia University, New York, October 1999. Download Article

Tan, Gabriel, Dao, Tam K., Smith, Donna L., Robinson, Andrew and Jensen, Mark P. Incorporating complementary and alternative medicine (CAM) therapies to expand psychological services to veterans suffering from chronic pain. Psychological Services. 2010; 7(3):148–161. Download Article

Holubec, Jerry T. Cumulative response from cranial electrotherapy stimulation (CES) for chronic pain Practical Pain Management. 2009; 9(9):80-83. Download Article

Click here to see a complete Alpha-Stim bibliography with annotated abstracts and the published studies

Let us help you get started! To have an Alpha-Stim representative contact you, complete the following form:

We offer free trials to practitioners for in-office use. Typically, an in-office or clinic trial can identify those individuals who readily respond to Alpha-Stim treatment. You or your patients can fulfill your order from our online store.

For more questions or details on special practitioner pricing, contact us at 1-(800) FOR-PAIN (in the US), + (940) 328-0788 (outside the US) or by emailing us at info@epii.com. You may also fax your order to us at +(940) 328-0888.

  • This field is for validation purposes and should be left unchanged.
  1. Heffernan M. Comparative effects of microcurrent stimulation on EEG spectrum and correlation dimension. Integrative Physiological and Behavioral Science. 1996; 31(3):202-209.
  2. Kennerly R. Changes in quantitative EEG and low resolution tomography following cranial electrotherapy stimulation. PhD Dissertation, the University of North Texas. 2006;529 pp., 81 tables, 233 figures, 171 references.